In Review / Planned
In Review (Pg. 1/2)
Might geographic disparities in social determinants of health enrich our understanding of pharmacologic risk factors for non-AIDS defining cancers among individuals with HIV infection.
Govt. Funding: NIH National Cancer Institute (NCI)
Grant Type: NCI Administrative Supplements for Geospatial, Multilevel, and Contextual Approaches in Cancer Control and Population Sciences
Planned Submission: May 2019
Expected Role (Effort): Project Lead (20%) PI: Chiao E (BCM)
Expected Period: 08/01/2019 to 06/30/2020
[modal_window title="GIS OF NON-AIDS CANCERS IN VA POPULATION" invoke_title="PROJECT BRIEF" id="gis-nonaids-cancers" show_on_load=""]Analysis proposed in this supplement will further the currently funded aims by integrating social determinants of health data measured at the census tract geographic level to data that have already been collated from the parent study activities. The specific aims are: (1) To further understand the context in which any relationships between pharmacologic risk factors and non-AIDS defining cancers occur; that is, determine whether or not neighborhood socioeconomic disadvantage, through ADI, differentially (positively and negatively) modifies the observed effect of pharmacologic risk factors on disease status and (2) To model spatial variation in the relationship between pharmacologic risk factors and non-AIDS defining cancers.
Access FOA Here.[/modal_window]
Reducing Disparities in the Risk of Hepatocellular Cancer In Texas.
Govt. Funding: Cancer Prevention and Research Institute of Texas (CPRIT)
Grant Type: Academic Research Award
Submitted: January 2019
Expected Role (Effort): Co-I (10%); PI: Kanwal F (BCM)
Expected Period: 08/01/2019 to 07/31/2025
[modal_window title="REDUCING LIVER CANCER DISPARITIES IN TEXAS" invoke_title="PROJECT BRIEF" id="txliver-cancer-disparities" show_on_load=""]Data related to the HCC incidence and outcomes in Texas underscore the urgency of addressing disparities in the HCC risk and prognosis in Texas. Yet, clinical interventions and policies to close these gaps have lagged behind. This is because fundamental questions about how disparities arise remain unanswered. Without a clear understanding about what to target, clinical care and outreach efforts to close these gaps will continue to struggle. The CPRIT identified a need for interventions to reduce disparities in HCC as a high priority. The proposed study addresses this priority.[/modal_window]
(RESUBMISSION) Multi-Level Evaluation of Racial/Ethnic and Socioeconomic Disparities in Liver Disease Outcomes.
Govt. Funding: National Institute of Health (NIH)
Grant Type: NIH Research Project Grant (R01)
Submitted: April 2019
Expected Role (Effort): Co-I (10%); PI: Kanwal F (BCM)
Expected Period: 02/01/2020 to 01/31/2025
[modal_window title="DISPARITIES IN CIRRHOSIS OUTCOMES" invoke_title="PROJECT BRIEF" id="disparities-cirrhosis-resubmit" show_on_load=""]Cirrhosis, a condition with high morbidity and mortality, is becoming increasingly common. Also, cirrhosis complications disproportionately affect racial/ethnic minorities and persons of low socioeconomic status (SES). The first key step towards eliminating substantial and growing disparities in cirrhosis prognosis is to understand the key factors contributing to these disparities. The proposal seeks to characterize the relative and absolute contributions of factors that drive these racial/ethnic and socioeconomic disparities using the National Institutes of Minority Health and Health Disparities (NIMHD) Framework, which attributes health disparities to biological, behavioral, sociocultural, and healthcare factors at the individual patient, interpersonal, and community levels.[/modal_window]
Planned (Pg. 2/2)
The impact of changes in space and time of residence on the incidence and severity of cardiometabolic late effects among a cohort of childhood cancer survivors.
Govt. Funding: NIH National Cancer Institute (NCI)
Grant Type: NIH Research Project Grant (R01)
Planned Submission: June 2019
Expected Role (Effort): Co-PI (%TBD) with Lupo P (BCM)
Expected Period: 04/01/2020 to 03/31/2025
[modal_window title="RESIDENTIAL HISTORIES & CHILDHOOD CANCER SURVIVORS" invoke_title="PROJECT BRIEF" id="resid-history-childcancer" show_on_load=""]The purpose of this Funding Opportunity Announcement (FOA) is to support substantive investigation of the role of individual residential histories in cancer etiology and outcomes, and to encourage the development of complex analytical strategies in support of substantive investigation. The overall goal of the proposed study is to assess the impact of changes in space and time of residence over 15 years on the incidence and severity of cardiometabolic late effects among a cohort of childhood cancer survivors. Aim 1 will assess space-time clustering of specific cardiometabolic outcomes. Aim 2 will create indices that represent burden of socioenvironmental exposures over time and place. Aim 3 will examine relationships between space/time-dependent exposures and outcomes using appropriate statistical protocols, including spatial survival analysis. Exploratory Aim will examine questions about gene-environment interactions.
Access FOA Here.[/modal_window]
A Multilevel Approach to Understanding Geographic Disparities in Increased Incidence of Hepatocellular Cancers in Texas.
Govt. Funding: NIH (TBD)
Grant Type: NIH Research Project Grant (R01)
Planned Submission: October 2019
Expected Role (Effort): Co-PI (%TBD) with Thrift A (BCM)
Expected Period: 07/01/2020 to 06/30/2025